NCT07391254

Omega-3 Supplementation and Mental Health in College Students

Impact of Omega-3 Supplementation on Omega-3 Status, Vitamin D and Mood in College Students

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 103 (actual)
• Sponsor: University of Colorado, Colorado Springs · Academic / Other
• Sex: All
• Age: 18 Years – 27 Years
• Healthy volunteers: Accepted

Summary

This randomized, placebo-controlled double blinded study examined whether placebo, low- or high dose omega 3 fatty acid supplementation had associations with mental health symptoms and vitamin D status in college students aged 18-27.

Detailed description

A 3-arm randomized design was employed where participants took 2 pills daily for 90 days. The first arm was a placebo, second arm was a low dose omega 3 and third arm was high dose omega 3. Mental health outcomes were measured using the GAD 7 questionnaire that measured anxiety, PHQ-9 which measured depression, and MSQ (Medical Symptoms Questionnaire) that assessed overall bodily symptoms. Vitamin D levels were also assessed as a secondary outcome.

Conditions

• Mental Health
• Vitamin D

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo	Placebo
DIETARY_SUPPLEMENT	Low dose Omega 3	700 mg/day omega 3 fatty acids
DIETARY_SUPPLEMENT	High dose Omega 3	2150 mg/day omega 3 fatty acids

Timeline

• Start date: 2024-08-29
• Primary completion: 2025-12-12
• Completion: 2025-12-12
• First posted: 2026-02-05
• Last updated: 2026-03-10

Locations

1 site across 1 country: United States