NCT07390812

Respiratory Transition Without Continuous Positive Airway Pressure

Respiratory Transition Without Continuous Positive Airway Pressure in Term Infants With Mild Respiratory Distress: A Pilot Study

• Status: Active Not Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Hackensack Meridian Health · Academic / Other
• Sex: All
• Age: 37 Weeks – 41 Weeks
• Healthy volunteers: Not accepted

Summary

The primary aim of this research project is to determine if term neonates (37:0 to 41:6 weeks' gestational age) with mild respiratory distress can safely transition without continuous positive airway pressure (CPAP). The secondary aim is to determine the incidence of pneumothorax (PTX) for all term neonates assessed to have mild respiratory distress in the delivery room (DR).

Conditions

• Mild Respiratory Distress

Interventions

Type	Name	Description
OTHER	Transition without Continuous Positive Airway Pressure (CPAP)	Allowing transition without CPAP administration was assessed at 25 minutes of life
OTHER	CPAP	CPAP administration as per standard of care

Timeline

• Start date: 2023-01-11
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2026-02-05
• Last updated: 2026-02-27

Locations

1 site across 1 country: United States