Trials / Not Yet Recruiting
Not Yet RecruitingNCT07389941
Semaglutide PrIor to CathEeter Ablation in Patients With Atrial Fibrillation
Semaglutide PrIor to CathEeter Ablation in Patients With Atrial Fibrillation (SPICE-AF)
- Status
- Not Yet Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 240 (estimated)
- Sponsor
- University of Luebeck · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate whether pre-treatment with semaglutide is superior to standard care in improving freedom from atrial fibrillation (AF) at 12 months following catheter ablation in patients with obesity and symptomatic AF undergoing first-time ablation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Semaglutide (SEMA) | Catheter ablation for AF plus semaglutide (up to 2.4 mg weekly) |
Timeline
- Start date
- 2026-10-01
- Primary completion
- 2029-04-01
- Completion
- 2029-04-01
- First posted
- 2026-02-05
- Last updated
- 2026-02-11
Source: ClinicalTrials.gov record NCT07389941. Inclusion in this directory is not an endorsement.