NCT07389798

Remimazolam TIVA-Flumazenil Antagonism in Short-duration ENT Surgeries

Effect of Remimazolam Total Intravenous Anesthesia-flumazenil Antagonism Guided by Different Target Range for the Bispectral Index in Short-duration Ear Nose Throat Surgeries: A Retrospective Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 600 (estimated)
• Sponsor: Tongji Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism based on whether their intraoperative BIS values were maintained below 60.

Detailed description

This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism into two groups based on whether their intraoperative BIS values were maintained below 60. It aims to compare the differences in postoperative recovery quality between the groups, thereby providing evidence-based support for determining the optimal BIS target range during remimazolam TIVA.

Conditions

• Remimazolam
• Total Intravenous Anesthesia
• Bispectral Index

Timeline

• Start date: 2026-02-01
• Primary completion: 2026-02-28
• Completion: 2026-03-31
• First posted: 2026-02-05
• Last updated: 2026-03-03