NCT07388797

Impact of Serum Progesterone Levels on Embryo Transfer Day on Clinical Pregnancy

Impact of Serum Progesterone Levels on Embryo Transfer Day on Clinical Pregnancy in Frozen-thawed Embryo Transfer Cycles Using Hormone Replacement Therapy: a Prospective Observational Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 370 (estimated)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: Female
• Age: 18 Years – 42 Years
• Healthy volunteers: Not accepted

Summary

Hypotheses: We hypothesize that serum progesterone levels on the day of embryo transfer in HRT-FET cycles are positively associated with clinical pregnancy rates. Aims: To evaluate the relationship between serum progesterone levels on embryo transfer day and clinical pregnancy outcomes in frozen-thawed embryo transfer cycles using hormone replacement therapy (HRT). Primary outcome: To compare the incidence of clinical pregnancy outcome in those infertility patients undergoing frozen embryo transfer with caterized Progesterone level on the day of embryo transfer Secondary outcomes: Biochemical pregnancy rate. Implantation rate. Early pregnancy loss rate. Ectopic pregnancy rate.

Conditions

• Reproductive Issues

Timeline

• Start date: 2026-02-10
• Primary completion: 2028-06-30
• Completion: 2028-12-31
• First posted: 2026-02-05
• Last updated: 2026-02-11

Locations

1 site across 1 country: China