NCT07385261

Treatment Strategy for Complicated Pediatric Appendicitis Based on Laparoscopic Surgery

Treatment Strategy for Complicated Pediatric Appendicitis Based on Laparoscopic Surgery. Ten Years of Multicenter Cohort Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 765 (actual)
• Sponsor: Mohammad Daboos · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Observational retrospective study included 765 children with Operative management by laparoscopic appendectomy, conservative management for appendicular mass and drainage of abscess by IR should be tried first. Interval appendectomy is reserved only for patients with recurrent symptoms. the study collect the Diagnostic data ,intraoperative and post operative data to submit the strategies of laparoscopic management in limited resources setting.

Detailed description

Background and study aims: In children with complicated appendicitis significant morbidity exists with prolonged hospitalization and increased costs. The management strategy for complicated pediatric appendicitis differs depending on facility resources together with surgeon's experience. Various studies investigated the usefulness of laparoscopic than open surgery even in complicated appendicitis. However, the treatment strategy remains controversial, especially in appendicular mass as well as appendicular abscess. Methods: This observational study included 765 children with complicated appendicitis. over 10 years period. Patients' demographics, clinical criteria for different presentations of complicated appendicitis, diagnostic work up, plans of treatment based on laparoscopic management were reviewed and analyzed regarding different variables and postoperative outcomes.

Conditions

• Appendix Diseases
• Surgery

Interventions

Type	Name	Description
PROCEDURE	laparoscopic appendectomy	Based on clinical findings, imaging studies and laboratory findings, after resuscitation, the decision of urgent surgery was according to the presentation Free peritoneal perforation (FPA) Perforated appendicitis with free peritoneal fluid were managed by urgent laparoscopic exploration Appendicular mass (AM) In patients presented by early mass formation lap exploration was carried out but trial of conservative management was planned for cases presented late with expected difficulty in lap dissection depending on surgical team and parental consultation, this accomplished by (nothing per mouth, I V fluid, I V antibiotic, temperature chart with U/S and biomarker follow up) Appendicular abscess (AAbs) Percutaneous drainage by availability IR team was the first choice however lap exploration and /or lap assisted extraperitoneal drainage was the second choice if IR failed or not available.

Timeline

• Start date: 2015-01-01
• Primary completion: 2025-01-01
• Completion: 2026-01-01
• First posted: 2026-02-04
• Last updated: 2026-02-04

Locations

1 site across 1 country: Egypt