NCT07384819

Duration of Moment in Autism

Evaluation of Visual Perception Development in Autism: Duration of a Moment

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 228 (estimated)
• Sponsor: Hôpital le Vinatier · Academic / Other
• Sex: All
• Age: 36 Months – 71 Months
• Healthy volunteers: Accepted

Summary

This study investigates the temporal dynamics of perception and attention in children with Autism Spectrum Disorder (ASD), focusing on two key phenomena: the Temporal Integration Window (TIW) and the attentional blink. Using eye-tracking, 3- and 5-year-old children with ASD (prototypical or not) will be compared to age-matched neurotypical peers. The investigators hypothesize that children with ASD exhibit shorter TIWs and attentional blinks, reflecting faster perceptual sampling and attentional processing. These characteristics may contribute to sensory hypersensitivity and difficulties in complex, unpredictable environments such as social situations. The protocol includes two experimental tasks.

Detailed description

The study is a multicenter research project that aims to investigate the temporal dynamics of visual perception and attention in children with Autism Spectrum Disorder (ASD), including both prototypical and non-prototypical subgroups. It compares these groups to age-matched neurotypical peers. The study focuses on two distinct cognitive phenomena: Temporal Integration Window (TIW) : a pre-attentive perceptual mechanism that determines the time frame within which visual information is integrated into a unified percept. In typically developing adults, this window is estimated to be around 65 milliseconds. Prior research suggests that children with ASD may have a shorter TIW, indicating faster perceptual sampling. Attentional Blink (AB) : a post-perceptual phenomenon reflecting limitations in attentional resources. When two targets are presented in rapid succession, the second target is often missed if it follows too closely after the first. The duration of the attentional blink is thought to decrease with age and maturation. Previous studies have shown that attentional blink is already present at 5 months of age and shortens during development. The central hypothesis is that both TIW and AB durations might be shorter in children with ASD, reflecting faster perceptual and attentional processing. This accelerated dynamic could contribute to sensory hypersensitivity and difficulty coping with complex or unpredictable environments, such as those involving social stimuli. A total of 228 children will participate, divided into six groups. Each participant will complete two eye-tracking tasks during a single session lasting approximately one hour: * The TIW task * The Attentional Blink task Developmental level is assessed using validated tools: the Mullen Scales of Early Learning, VINELAND-2 or the IDE questionnaire, depending on the child's group. The study will also examine whether the prototypical ASD subgroup, as defined by clinical criteria shows distinct perceptual profiles, and whether age or developmental level influences temporal dynamics. This study aims to better understand early perceptual and attentional processes in autism.

Conditions

• Autism Spectrum Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Temporal Integration Window task	The TIW task involves alternating visual displays (integration and segmentation trials) across four inter-stimulus intervals (ISI: 16, 32, 83, 116 ms). This task allows estimation of the participant's perceptual integration threshold.
BEHAVIORAL	Attentional Blink task	The Attentional Blink task presents rapid sequences of images (including two targets and distractors), measuring the minimum time delay required for both targets to be detected. Three different T1-T2 intervals are tested.

Timeline

• Start date: 2026-02-16
• Primary completion: 2028-08-16
• Completion: 2028-08-16
• First posted: 2026-02-03
• Last updated: 2026-02-05

Locations

2 sites across 1 country: France