NCT07384663

EFFICACY OF IV VERSUS ORAL IRON IN THE TREATMENT OF IRON DEFICIENCY ANEMIA DURING PREGNANCY

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: Dr Salaha Azam · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This study was planned to compare outcomes of IV versus oral iron in the treatment of iron deficiency anemia during pregnancy. This study was used to investigate the efficacy of two new formulations of iron both in IV and oral form with fewer side effects. We compared the efficacy of Intravenous Ferric Carboxymaltose with Oral polysaccharide iron complex. The better mode of treatment will be administered in future to treat this condition, that will surely improve the fetal and maternal outcome.

Conditions

• Iron Deficiency Anaemia in Childbirth

Interventions

Type	Name	Description
DRUG	Iron Carboxymaltose	Single dose of 500 mg Ferric carboxymaltose diluted in 100 mL 0.9% sodium chloride (or if pre-pregnancy body weight is \< 50 kg the dose was 10 mg/kg based on pre-pregnancy body weight). Infusions was administered over approximately 20 min and participants were observed for adverse reactions during, and 30 min after, the end of the infusion.
DRUG	Iron Polymaltose Complex	Polysaccharide iron complex 150 mg capsule was administered daily till 4 weeks

Timeline

• Start date: 2025-06-01
• Primary completion: 2025-11-30
• Completion: 2025-11-30
• First posted: 2026-02-03
• Last updated: 2026-02-03

Locations

1 site across 1 country: Pakistan