NCT07381062

Total Knee Arthroplasty in Conjunction With Intra-operative Genicular Nerve Radio-Frequency Ablation

Total Knee Arthroplasty in Conjunction With Intra-operative Genicular Nerve Radio-Frequency Ablation, A Randomized Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare between conventional Total Knee Arthroplasty (TKA) and Total Knee Arthroplasty (TKA) combined with intra-operative Genicular Nerve Radio-Frequency Ablation (GNRFA), concerning post-operative functional outcome and pain scores in patients with advanced knee osteoarthritis

Detailed description

The aim of this study is to compare between conventional Total Knee Arthroplasty (TKA) and Total Knee Arthroplasty (TKA) combined with intra-operative Genicular Nerve Radio-Frequency Ablation (GNRFA), concerning post-operative functional outcome and pain scores in patients with advanced knee osteoarthritis Including 70 knees randomized using a computer-generated sequence into two groups, the first group underwent TKA combined with GNRFA, and the other group underwent TKA only. All the TKA surgeries were performed by a single surgeon including patients aged from fifty to eighty years with advanced primary knee osteoarthritis from both sexes

Conditions

• Post Operative Pain
• Functional Outcome

Interventions

Type	Name	Description
PROCEDURE	Total knee arthroplasty	Conventional Total knee arthroplasty operation performed
PROCEDURE	Genicular nerve radiofrequency ablation	Genicular nerve radiofrequency ablation done with no modifications except being performed with total knee arthroplasty in the same setting

Timeline

• Start date: 2022-02-22
• Primary completion: 2024-03-04
• Completion: 2024-10-01
• First posted: 2026-02-02
• Last updated: 2026-02-11

Locations

1 site across 1 country: Egypt