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Enrolling By InvitationNCT07376629

A Study of HB0025 Plus Nab-paclitaxel as First Line Therapy for TNBC

A Phase II Study of HB0025 in Combination With Nab-Paclitaxel as First Line Therapy for Unresectable, Locally Advanced or Metastatic Triple-negative Breast Cancer.

Status
Enrolling By Invitation
Phase
Phase 2
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
Huabo Biopharm Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This trial is a Phase II study. The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of HB0025 administered with chemotherapy in participants with locally advanced or metastatic triple-negative breast cancer (TNBC) who have not received prior systemic therapy for metastatic breast cancer (mBC).

Conditions

Interventions

TypeNameDescription
DRUGHB0025 20 mg/kg plus nab-paclitaxelHB0025 20 mg/kg
DRUGHB0025 10 mg/kg plus nab-paclitaxelHB0025 10 mg/kg

Timeline

Start date
2025-08-14
Primary completion
2027-01-15
Completion
2027-01-15
First posted
2026-01-29
Last updated
2026-01-29

Locations

23 sites across 1 country: China

Source: ClinicalTrials.gov record NCT07376629. Inclusion in this directory is not an endorsement.