NCT07374822

Real-World Study of Helicobacter Pylori Eradication Success and Its Determinants

Study on the Real-World Eradication Success Rate of Helicobacter Pylori Infection and Its Influencing Factors

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,000 (actual)
• Sponsor: Run-hua Li · Academic / Other
• Sex: All
• Age: 14 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the real-world effectiveness of different treatment regimens used to eradicate Helicobacter pylori (H. pylori) infection in routine clinical practice. H. pylori is a common bacterial infection that can lead to chronic gastritis, peptic ulcers, and gastric cancer. Treatment success varies widely in real-world settings due to factors such as antibiotic resistance, patient characteristics, and treatment adherence. This retrospective observational study will review medical records of patients who underwent H. pylori testing and/or eradication treatment at Shenzhen Hospital of Southern Medical University between 2016 and 2023. No additional tests, visits, or interventions will be performed beyond standard clinical care. The study will collect information on demographics, comorbidities, treatment regimens, test results, and eradication outcomes. The primary goal is to determine the real-world eradication success rate of commonly used treatment regimens. A secondary goal is to identify factors that may influence treatment effectiveness. Findings from this study may help clinicians choose more effective treatment strategies and improve patient outcomes in everyday clinical practice.

Conditions

• HELICOBACTER PYLORI INFECTIONS

Interventions

Type	Name	Description
OTHER	No Study-Assigned Intervention	Participants receive standard-of-care H. pylori eradication regimens as determined by their treating physicians. The study does not assign or modify any treatment. Data are collected retrospectively from routine clinical records.

Timeline

• Start date: 2024-05-01
• Primary completion: 2025-05-31
• Completion: 2025-05-31
• First posted: 2026-01-29
• Last updated: 2026-01-29

Locations

1 site across 1 country: China