NCT07374393

Establishment of a Sleep and Sleep-disorder Research Cohort in Patients With Neurological Disorders

Establishment of a Research Cohort on Sleep and Sleep Disorders in Patients With Neurological Diseases

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: The First Hospital of Jilin University · Academic / Other
• Sex: All
• Age: 14 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study aims to establish a research cohort on sleep and sleep disorders in patients with neurological diseases to systematically evaluate the relationship between various neurological conditions and sleep characteristics or disturbances.

Detailed description

The cohort will include patients with confirmed diagnoses such as stroke, Parkinson's disease, epilepsy, cognitive disorders, neuroinfections, and immune-mediated neurological diseases, with collection of demographic data, medical history, and lifestyle factors. All participants will undergo standardized polysomnography (PSG), sleep questionnaires, assessments of cognition, mood, daytime function, as well as relevant imaging and laboratory tests. Designed as a prospective observational study, the cohort will focus on sleep architecture alterations, periodic limb movements, sleep-disordered breathing, REM sleep behavior disorder, nocturnal awakenings, heart rate, and oxygen saturation, and their associations with disease severity and progression. The data will provide a basis for exploring the mechanisms, early indicators, and potential interventions for sleep disturbances in neurological patients.

Conditions

• Sleep
• Neurology

Interventions

Type	Name	Description
OTHER	Symptomatic and Etiological Treatment	sleep-related

Timeline

• Start date: 2026-01-04
• Primary completion: 2028-12-31
• Completion: 2030-12-31
• First posted: 2026-01-28
• Last updated: 2026-01-28

Locations

1 site across 1 country: China