NCT07371975

A Study to Evaluate the Effects of a Butyrate-Polyphenol Formulation on Gut Health and Associated Symptoms

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 124 (estimated)
• Sponsor: Supplement Formulators, Inc. · Industry
• Sex: All
• Age: 25 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to evaluate the efficacy of a butyrate/polyphenol formulation on modulation of the gut microbiome and gastrointestinal symptoms using questionnaires in individuals with self-reported gastrointestinal discomfort.

Detailed description

This is a double-blind, randomized, placebo-controlled study to evaluate the effects of a butyrate/polyphenol formulation on gut health and associated symptoms in healthy individuals. Participants will be asked to complete a laboratory assessment and questionnaires. A total of up to 124 subjects (62 subjects per arm) will be enrolled for the 14-day period. Laboratory testing will include an assessment of the Gut Microbiome.

Conditions

• Gut Health

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Butyrate + Polyphenol Formulation	Butyrate + Polyphenol Formulation
DIETARY_SUPPLEMENT	Placebo	Placebo

Timeline

• Start date: 2025-10-16
• Primary completion: 2026-04-26
• Completion: 2026-07-30
• First posted: 2026-01-28
• Last updated: 2026-01-29

Locations

1 site across 1 country: United States