Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07369986

Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer

A Phase 2b, Open-Label Study of Iparomlimab and Tuvonralimab to Facilitate Surgery Avoidance in Women With Resectable, Mismatch Repair-Deficient Endometrial Cancer

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Women's Hospital School Of Medicine Zhejiang University · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

Efficacy evaluate of iparomlimab and tuvonralimab (a PD-1/CTLA-4 bispecific antibody) in patients with surgically resectable dMMR endometrial cancer.

Conditions

Interventions

TypeNameDescription
DRUGIparomlimab and Tuvonralimab (QL1706)Iparomlimab and Tuvonralimab as a strategy to facilitate non-surgical management in women with surgically completely resectable dMMR endometrial cancer.

Timeline

Start date
2026-03-01
Primary completion
2027-12-31
Completion
2028-12-31
First posted
2026-01-27
Last updated
2026-01-27

Source: ClinicalTrials.gov record NCT07369986. Inclusion in this directory is not an endorsement.