NCT07369388

Endothelial Changes in Diabetic and Non-diabetic Patients Undergoing Phacoemulsification

Specular Endothelial Changes in Diabetic and Non-diabetic Patients Undergoing Phacoemulsification

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate and compare specular endothelial changes in diabetic and non-diabetic patients undergoing phacoemulsification by assessing endothelial cell density, coefficient of variation, and percentage of hexagonal cells preoperatively and postoperatively. This study also seeks to provide updated evidence on the influence of diabetes on corneal endothelial response to cataract surgery and to support evidence-based strategies for optimizing surgical outcomes

Conditions

• Endothelial Cell Density Loss

Interventions

Type	Name	Description
PROCEDURE	Phacoemulsification	Cataract surgery using phacoemulsification is the most frequently performed ophthalmic procedure worldwide and is considered a highly effective and safe method for visual rehabilitation

Timeline

• Start date: 2025-05-01
• Primary completion: 2026-01-15
• Completion: 2026-01-17
• First posted: 2026-01-27
• Last updated: 2026-01-27

Locations

1 site across 1 country: Egypt