NCT07368114

Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft

Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft on Osseointegration of Immediate Dental Implants

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Suez Canal University · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant. The aim of this study is to evaluate clinically and radiographically the efficacy of injectable bone graft versus ozonated olive oil gel to promote bone formation and improve outcomes in immediate implant cases. 16 immediate implants will be placed in mandibular premolar region the study will be devided equally and randomlly into two groups , Group 1: it will be 8 immediate implants represent the control group were the implants will be placed with injectable bone graft , Group 2: will be 8 immediate implant represent the study group were the implants will be placed with ozonated olive oil gel be used as a graft material . The implant stability will be assessed clinically using Ostell , and the bone density will be assed radiographically .

Conditions

• Dental
• Implant Osseointegration
• Ozone Therapy
• Bone Graft

Interventions

Type	Name	Description
PROCEDURE	Immediate implant placement	Placement of a dental implant immediately after tooth extraction in the mandibular premolar region following standard surgical protocol.
BIOLOGICAL	β-tricalcium phosphate Injectable Bone Graft	Immediate implant placement in the mandibular premolar region with application of injectable bone graft material to the peri-implant defect.
BIOLOGICAL	Ozonated olive oil gel	Immediate implant placement in the mandibular premolar region with application of ozonated olive oil gel to the peri-implant defect.

Timeline

• Start date: 2023-12-10
• Primary completion: 2025-05-10
• Completion: 2025-09-10
• First posted: 2026-01-26
• Last updated: 2026-01-26

Locations

1 site across 1 country: Egypt