NCT07367568

Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy

Comparison of Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy: A Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 110 (estimated)
• Sponsor: National Cancer Institute, Egypt · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare the costotransverse foramen block with erector spinae plane block in modified radical mastectomy.

Detailed description

Postoperative pain following modified radical mastectomy (MRM) is a considerable consequence, impacting the ipsilateral upper limbs, axillae, and thorax, resulting in diminished functional ability and substantial economic and societal repercussions. Erector spinae plane block (ESPB), an interfascial block, minimizes nerve and vessel injury by allowing local anesthetics to diffuse across relevant spaces; it is technically simpler and has shown benefits in reducing postoperative analgesic use and pain scores. A novel technique, the costotransverse foramen block (CTFB), is one type of Inter-transverse process (ITP) blocks. This technique entails the anterior dispersion of the local anesthetic injectate into the paravertebral region, affecting the thoracic nerve at the injection site and neighboring levels, while exhibiting negligible posterior diffusion of dye to the deep back muscles

Conditions

• Costotransverse Foramen Block
• Erector Spinae Plane Block
• Modified Radical Mastectomy

Interventions

Type	Name	Description
OTHER	Costotransverse foramen block	Patients will receive an ipsilateral ultrasound-guided costotransverse foramen block with injection of 20 ml bupivacaine 0.25%.
OTHER	Erector spinae plane block	Patients will receive an ipsilateral ultrasound-guided erector spinae plane block with injection of 20 ml bupivacaine 0.25%.

Timeline

• Start date: 2026-01-24
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2026-01-26
• Last updated: 2026-01-27

Locations

1 site across 1 country: Egypt