NCT07367204

Randomized Masked Trial of Injectable Cross-Linked Hyaluronic Acid for Moderate-to-Severe Nasolabial Folds

A Prospective, Multicenter, Randomized, Parallel-Controlled, Subject- and Investigator-Masked, Non-Inferiority Clinical Trial to Evaluate the Efficacy and Safety of Cross-Linked Hyaluronic Acid Gel for Injection in Correcting Moderate to Severe Nasolabial Folds

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 356 (actual)
• Sponsor: Chongqing Jinsaixing Medical Technology Co., Ltd · Industry
• Sex: All
• Age: 26 Years
• Healthy volunteers: Not accepted

Summary

The objective of this clinical trial is to evaluate the efficacy and safety of injectable cross - linked hyaluronic acid gel for correcting moderate to severe nasolabial fold wrinkles, on the premise of ensuring the safety of subjects and the scientific rigor of the clinical trial.

Conditions

• Nasolabial Fold Wrinkles

Interventions

Type	Name	Description
DEVICE	Intense	Correction of moderate to severe nasolabial fold wrinkles
DEVICE	Restylane	the Correction of Midface Volume Deficiency and/or Midface Contour Deficiency

Timeline

• Start date: 2025-02-24
• Primary completion: 2026-04-26
• Completion: 2027-03-06
• First posted: 2026-01-26
• Last updated: 2026-01-26

Locations

1 site across 1 country: China