NCT07366762

Comparison Between Two Techniques in Treatment of Female Stress Urinary Incontinence

Comparison Between the Effect of Periurethral Injection of Platelet-rich Plasma VS Platelet Rich Fibrin in Treatment of Female Stress Urinary Incontinence

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Kafrelsheikh University · Academic / Other
• Sex: Female
• Age: 30 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

compare the therapeutic effect of periurethral injection of autologous platelet-rich plasma (PRP) and injectable platelet rich fibrin (i-PRF) in treatment of female stress urinary incontinence and comparing the need for re-injection in the two groups.

Conditions

• Female Stress Urinary Incontinence

Interventions

Type	Name	Description
BIOLOGICAL	Platelet Rich Plasma	Approximately 5 mL of PRP will be injected at three points (on both sides of the urethra and urethrovaginal space) under local anesthesia. Injections will be performed by gynecologist in the outpatient clinic.
BIOLOGICAL	Platelet rich fibrin	Approximately 5 mL of i-PRF will be injected at three points (on both sides of the urethra and urethrovaginal space) under local anesthesia. Injections will be performed by gynecologist in the outpatient clinic

Timeline

• Start date: 2024-07-10
• Primary completion: 2025-05-01
• Completion: 2026-01-02
• First posted: 2026-01-26
• Last updated: 2026-01-26

Locations

1 site across 1 country: Egypt