NCT07366398

Hyaluronic Acid Mouthwash as Adjunct

Hyaluronic Acid as Adjunctive to Chlorhexidine Mouthwash for Gingivitis: RCT

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 25 Years
• Healthy volunteers: Not accepted

Summary

Patients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.

Detailed description

The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients. Patients were randomly assigned to either control group received (Chlorhexidine mouthwash) or test group received (hyaluronic acid + Chlorhexidine mouthwash). Clinical parameters and patient reported outcomes as post-operative questionnaire were assessed at baseline and seven days post-operatively.

Conditions

• Gingivitis; Chronic

Interventions

Type	Name	Description
DRUG	Hyaluoric acid mouthwash	A mouthwash containing both hyaluronic acid
DRUG	Chlorhexidine 0,12%	mouthwash of chlorhexidine 0.12%

Timeline

• Start date: 2025-02-01
• Primary completion: 2025-05-30
• Completion: 2025-05-30
• First posted: 2026-01-26
• Last updated: 2026-01-26

Locations

1 site across 1 country: Egypt