NCT07364149

Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults

Acute Effects of Structured Physical Exercise and Static Passive Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation: A Randomized Crossover Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (estimated)
• Sponsor: University of Palermo · Academic / Other
• Sex: Male
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition. Participants are allocated to one of three groups (control, resistance training, resistance training plus static stretching) and assessed at baseline, immediately after the session, and 30 minutes post-exercise. Primary outcomes include blood pressure and other hemodynamic or functional measures, in order to explore the short-term impact of these exercise modalities on cardiovascular regulation.

Conditions

• Healthy
• Healthy Participants
• Healthy Subjects (HS)
• Resistance Training Adaptation
• Static Stretching
• Stretch

Interventions

Type	Name	Description
OTHER	Resistance Training	Participants assigned to this group will complete a single supervised upper body resistance training session. The protocol includes bench presses and bicep curls performed at 80% of the individual's 1-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes. The total duration of the session is approximately 20-30 minutes and does not include any additional static stretching beyond the standardized warm-up.
OTHER	Resistance training + Static Stretching	Participants assigned to this group will complete a single supervised upper body resistance training session. The protocol includes bench presses and bicep curls performed at 80% of the individual's 1-rep max, for 4 sets of 8 reps, with standardized rest intervals between sets of 2 minutes. The total duration of the session is approximately 20-25 minutes .Immediately after the resistance exercises, they will complete a structured static stretching protocol targeting the trained muscle groups (pectoralis and elbow flexors), with each stretch held for about 30 seconds and repeated for several sets. The additional stretching lasts 12 minutes, for a total session duration of about 35-40 minutes.

Timeline

• Start date: 2025-12-15
• Primary completion: 2026-03-10
• Completion: 2026-03-10
• First posted: 2026-01-23
• Last updated: 2026-01-27

Locations

1 site across 1 country: Italy