Trials / Completed
CompletedNCT07362108
Cardiovascular Events Related to Treated Coronary Arteries in Stable Multivessel CAD
Cardiovascular Events Related to the Coronary Artery Treated by Surgical or Percutaneous Revascularization in Patients With Stable Multivessel Coronary Artery Disease: A Long-Term Comparison With Medical Therapy - Target Trial
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,695 (actual)
- Sponsor
- Instituto do Coracao · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This retrospective cohort study evaluates cardiovascular events directly related to treated coronary arteries in patients with stable multivessel coronary artery disease. Outcomes in patients undergoing coronary artery bypass grafting or percutaneous coronary intervention will be compared with those receiving optimized medical therapy alone. This study aims to improve understanding of how different treatment strategies impact long-term vessel-related outcomes in patients with stable multivessel coronary artery disease.
Detailed description
Previous studies evaluating coronary revascularization strategies have relied on broad composite endpoints, which may include events unrelated to the treated vessel. This study focuses on vessel-related outcomes, specifically non-fatal myocardial infarction and cardiac death attributable to the treated coronary artery. Patients were selected from the MASS (Medicine, Angioplasty, or Surgery Study) database at a single tertiary center. By analyzing vessel-specific events, this study aims to provide a more accurate assessment of the long-term impact of different treatment strategies in stable multivessel coronary artery disease.
Conditions
- Coronary Artery Disease
- Stable Coronary Artery Disease
- Multivessel Coronary Artery Disease
- Myocardial Ischemia
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Coronary Artery Bypass Grafting | Surgical myocardial revascularization using coronary artery bypass grafting. |
| PROCEDURE | Percutaneous Coronary Intervention | Percutaneous coronary intervention performed according to standard clinical practice. |
| OTHER | Optimized Medical Therapy | Guideline-directed medical therapy for stable coronary artery disease. |
Timeline
- Start date
- 1995-01-01
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
- First posted
- 2026-01-23
- Last updated
- 2026-01-23
Source: ClinicalTrials.gov record NCT07362108. Inclusion in this directory is not an endorsement.