NCT07360821

Investigation of Autonomic Stress Response Patterns in College Students With Varying Physical Activity Levels

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Beijing Sport University · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate the differences in cardiovascular stress response patterns among individuals with various physical activity levels (sedentary controls and different types of athletes). By synchronously monitoring ECG, heart rate, skin sympathetic nerve activity (SKNA), blood pressure, and cardiac output, the study will characterize physiological dynamics during resting, orthostatic challenge, cold pressor stress, and maximal exercise.

Detailed description

Participants will be categorized into five groups based on their training background: sedentary, endurance, strength, technical, and traditional ethnic sports. The experimental protocol includes baseline measurements in lying, standing, and sitting positions, followed by a series of acute stress tests: a lie-to-stand orthostatic test, a slow breathing test, and a cold pressor test. Finally, participants will perform a ramp incremental exercise test on a cycle ergometer. Synchronous physiological data including HRV and SKNA will be collected to evaluate the dynamic regulation of the autonomic nervous system.

Conditions

• Autonomic Nervous System Activity
• Cardiovascular
• Physical Activity Level

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardiopulmonary Exercise Testing	Cardiopulmonary Exercise Testing (CPET) is a non-invasive, integrated assessment of the cardiovascular, respiratory, and muscular systems' responses to physical stress.

Timeline

• Start date: 2026-02-25
• Primary completion: 2026-04-30
• Completion: 2026-07-30
• First posted: 2026-01-22
• Last updated: 2026-01-22