NCT07359911

Effect of A Multimodal Exercise Intervention on Chemotherapy Uptake in Newly Diagnosed Pediatric and AYA Sarcoma Patients

Effect of A Multimodal Exercise Intervention on Chemotherapy Uptake in Newly Diagnosed Pediatric and AYA Sarcoma Patients (ACTIVE-SARC)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 12 Years – 39 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the effects of a multimodal exercise intervention on chemotherapy uptake in newly diagnosed pediatric, adolescent and young adult (AYA) Sarcoma patients.

Conditions

• Sarcoma

Interventions

Type	Name	Description
BEHAVIORAL	Exercise Intervention	Each session will include a brief conversation and standardized symptom assessment, followed by a warm-up including stretching \& balance exercises, then a series of resistance exercises, ending with light-moderate intensity aerobic exercise (walking), with a target goal of 45-60 minutes total per session as tolerated by the patient.
BEHAVIORAL	Usual Care Control	A weekly brief symptom self-assessment as a survey will be delivered by Redcap survey, in person or remotely, or by telephone with researcher assistance. Completion of the survey will take approximately 10 minutes per week.
BEHAVIORAL	Exit Interview	A semi-structured interview will be administered at 12 weeks to the intervention (EXE) group only to explore self-determination and efficacy, as well as intervention acceptability.

Timeline

• Start date: 2026-02-05
• Primary completion: 2027-08-05
• Completion: 2027-08-05
• First posted: 2026-01-22
• Last updated: 2026-02-18

Locations

1 site across 1 country: United States