NCT07359508

Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter

Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Cholecystectomy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 146 (actual)
• Sponsor: All India Institute of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

effect of propofol vs desflurane on ONSD

Conditions

• Propofol Target-controlled Infusion
• Desflurane
• Optic Nerve Sheath Diameter

Interventions

Type	Name	Description
DRUG	Desflurane	In the D group, anesthesia was maintained with oxygen/air (40:60), desflurane, fentanyl and vecuronium
DRUG	Propofol (Group P)	In the P group, anesthesia was maintained with oxygen/air (40:60), propofol infusion @50 to 100mcg/kg/min, fentanyl and Vecuronium

Timeline

• Start date: 2024-01-10
• Primary completion: 2025-06-15
• Completion: 2025-07-15
• First posted: 2026-01-22
• Last updated: 2026-01-22

Locations

1 site across 1 country: India