NCT07358416

Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery.

Determination the Safety of Disaggregant and Anticoagulant Therapy in the Development of Complications in Noncardiac Vascular Surgery.

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Petrovsky National Research Centre of Surgery · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this retrospective clinical trial is to find out association antiplatelet and anticoagulant therapy with perioperative complications in non-cardiac vascular surgery in patients . The main questions it aims to answer are: Does the use of antiplatelet agents and anticoagulants affect the development of complications in the perioperative period during operations on the main arteries? Does discontinuing antiplatelet and anticoagulant medications affect the development of perioperative complications in major artery surgeries?? Researchers will compare with patients who didn't use antiplatelets and anticoagulant drugs to see ift he incidence of complications comparable? This is a retrospective study based on the analysis of medical records (case histories).

Conditions

• Thrombosis
• Bleeding
• Cerebral Hypoxia During and/or Resulting From A Procedure

Interventions

Type	Name	Description
DRUG	Aspirin	Patients who take aspirin until the operation day
DRUG	Clopidogrel	Patients who take clopidogrel until the operation day
DRUG	Ticagrelor	Patients who take ticagrelor until the operation day
DRUG	Dabigatran	Patients who take dabigatran until the operation day
DRUG	Rivaroxaban	Patients who take rivaroxaban until the operation day
DRUG	Apixaban	Patients who take apixaban until the operation day
DRUG	Warfarin	Patients who take warfarin until the operation day
DRUG	aspirin + clopidogrel	Patients who take aspirin and clopidogrel until the operation day
DRUG	Aspirin + Ticagrelor	Patients who take aspirin and ticagrelor until the operation day
DRUG	Aspirin + Apixaban	Patients who take aspirin and apixaban until the operation day
DRUG	Aspirin + rivaroxaban	Patients who take aspirin and rivaroxaban until the operation day
DRUG	Clopidogrel + Apixaban	Patients who take clopidogrel and apixaban until the operation day
DRUG	Clopidogrel + Rivaroxaban	Patients who take clopidogrel and rivaroxaban until the operation day

Timeline

• Start date: 2025-05-01
• Primary completion: 2026-02-12
• Completion: 2026-02-28
• First posted: 2026-01-22
• Last updated: 2026-01-22

Locations

1 site across 1 country: Russia