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Trials / Not Yet Recruiting

Not Yet RecruitingNCT07357948

Omission of Surgery for Triple-negative Breast Cancer in Complete Response After Neoadjuvant Chemo-immunotherapy

Omission of Surgery for Triple-negative Breast Cancer in Complete Response Confirmed by MRI and Macrobiopsy After Neoadjuvant Chemo-immunotherapy: a Randomized, Multicenter Phase II Trial.

Status
Not Yet Recruiting
Phase
N/A
Study type
Interventional
Enrollment
150 (estimated)
Sponsor
Institut Curie · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

This clinical study aims to determine if skipping breast and axillary surgery could provide similar control of local and distant disease, with fewer complications and better quality of life, for triple-negative breast cancer patients in complete response after neoadjuvant chemo-immunotherapy. Patients will be randomised into 2 groups : * Control arm will receive the standard treatment, including surgery * Experimental arm will receive the standard treatment, except surgery

Conditions

Interventions

TypeNameDescription
PROCEDUREOmission of surgeryPatients will not undergo breast and axillary surgery.

Timeline

Start date
2026-08-01
Primary completion
2031-07-31
Completion
2033-07-31
First posted
2026-01-22
Last updated
2026-01-22

Source: ClinicalTrials.gov record NCT07357948. Inclusion in this directory is not an endorsement.