NCT07356219

Prognostic Nutritional Index for Predicting Outcomes Following Coronary Artery Bypass Grafting (CABG) Surgery

The Merits of the Prognostic Nutritional Index for Prediction of the Outcome of Coronary Artery Bypass Grafting Surgery: A Retrospective Observational Study

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 117 (actual)
• Sponsor: Benha University · Academic / Other
• Sex: All
• Age: 25 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality. Malnutrition and inflammation are known independent risk factors for poor outcomes in patients with coronary artery disease. This retrospective observational study evaluates the Prognostic Nutritional Index (PNI)-a simple score derived from serum albumin and lymphocyte counts-as an objective measure of nutritional and inflammatory status. The research aims to determine how well preoperative PNI and its postoperative changes can predict complications such as acute kidney injury, myocardial infarction, and sternal wound infections in patients undergoing CABG.

Conditions

• Coronary Artery Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Prognostic Nutritional Index (PNI)	Calculated using serum albumin (g/L) and total peripheral lymphocyte count.
DIAGNOSTIC_TEST	Neutrophil-to-Lymphocyte Ratio (NLR)	Calculated from peripheral blood counts.
DIAGNOSTIC_TEST	Body Mass Index (BMI)	Calculated from preoperative weight and height.

Timeline

• Start date: 2025-11-15
• Primary completion: 2026-01-11
• Completion: 2026-01-20
• First posted: 2026-01-21
• Last updated: 2026-01-21

Locations

1 site across 1 country: Egypt