NCT07355816

Effect of Different Root Canal Disinfection Procedures on Postoperative Pain

Effect of Different Root Canal Disinfection Procedures on Postoperative Pain: A One-Week Follow-Up Clinical Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Cumhuriyet University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This clinical study evaluated the effects of different root canal disinfection procedures on postoperative pain. Patients requiring root canal treatment received one of several disinfection methods. Postoperative pain was assessed at 6,24, 48, 72 hours and on the 7th day using a standard pain scale. The aim of the study was to identify which method resulted in the least discomfort. Participation involved a single treatment session and short-term follow-up for pain measurement.

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
PROCEDURE	Conventional Needle Irrigation	Root canals will be irrigated using a conventional syringe and needle technique with standard irrigant solutions. This method relies solely on manual delivery without activation devices.
PROCEDURE	Passive Ultrasonic Irrigation	Root canals will be irrigated using passive ultrasonic activation, which uses ultrasonic energy to improve irrigant effectiveness and reduce microbial load beyond manual techniques.
PROCEDURE	Sonic Irrigation	Root canals will be irrigated using a sonic activation device (e.g., EndoActivator) to enhance irrigant penetration and bacterial elimination compared to conventional irrigation.
PROCEDURE	KTP Laser Disinfection	Root canals will be disinfected using a KTP laser following standard irrigation protocols. Laser application aims to provide enhanced antimicrobial effects not achievable with conventional or activated irrigation methods.

Timeline

• Start date: 2023-06-13
• Primary completion: 2024-11-11
• Completion: 2024-11-11
• First posted: 2026-01-21
• Last updated: 2026-01-21

Locations

1 site across 1 country: Turkey (Türkiye)