NCT07355530

Can Adipose Derived Regenrative Cells be Used for Treating Erectile Dysfunction After Radical Prostatectomy

A Randomized Double-blind, Placebo-controlled Trial of Adipose-derived Regenerative Cells Injected Into Corpora Cavernosum Following Radical Prostatectomy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Odense University Hospital · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

The goal of this study was to investigate if adipose derived regenerative cells can be used as a treatment for erectile dysfunction following radical prostatectomy. 70 participants were enrolled in the study and was performed as a double- blinded study. 35 participants in the active study arm recieved an injection into the penis of adipose derived regenerative cells, while the participants of the placebo arm recieved a placebo injection. All 70 participants undervent liposuccion of the abdomen to harvest the adipose derived regenerative cells, and the 35 participants in the active study arm recieved their own regenerative cells. All participants answered the questionnaires International-Index-of- Erectile function 5 and Erection Hardness Scale before treatment and after 1,3,6 and 12 months. These data was used to evaluate the effect of one injection of adipose derived regenerative cells.

Conditions

• ED
• Adipose Derived Stem Cells

Interventions

Type	Name	Description
DRUG	Adipose-Derived Regenerative Cells	Adipose-derived regenerative cells was injected into the corpus cavernosum.
OTHER	Placebo	Injection of ringer lactate

Timeline

• Start date: 2018-01-20
• Primary completion: 2021-03-03
• Completion: 2021-03-03
• First posted: 2026-01-21
• Last updated: 2026-01-21

Locations

1 site across 1 country: Denmark