NCT07352189

Ultrasound-Guided Versus Laparoscopy-Guided Transversus Abdominis Plane Block for Postoperative Analgesia

Comparison of the Efficacy of Ultrasound-Guided and Laparoscopy-Guided Transversus Abdominis Plane(TAP) Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Upper Abdominal Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Postoperative pain scores, analgesic consumption and recovery parameters were evaluated during the first 24 hours after surgery.

Detailed description

Patients aged 18-70 years with ASA physical status I-III who were scheduled for laparoscopic upper abdominal surgery under general anesthesia were included in the study. After induction of anesthesia, patients were randomly assigned to one of two group, bilateral subcostal transversus abdominis plane block was performed under ultrasound-guidance using a local anesthetic mixture before extubation. In the laparoscopy-guided group, bilateral subcostal transversus abdominis plane block was performed under laparoscopic guidance using the same local anesthetic mixture before abdominal closure. Postoperative pain intensity was assessed by using the Numeric Rating Scale (NRS). Total opioid consumption, time to first analgesic requirement, paracetamol consumption, postoperative nausea and vomiting, length of hospital stay, time to ambulation and time to gastrointestinal recovery were recorded during the first 24 hours after surgery. Complications related to the TAP block were also evaluated.

Conditions

• Postoperative Pain Management

Interventions

Type	Name	Description
PROCEDURE	Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block	Bilateral ultrasound-guided subcostal transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL0.25% bupivacaine and 10 ml of 1% lidocaine).
PROCEDURE	Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block	Bilateral laparoscopy-guided transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL 0.25% bupivacaine and 10 ml of 1% lidocaine).

Timeline

• Start date: 2023-01-11
• Primary completion: 2023-06-15
• Completion: 2023-06-15
• First posted: 2026-01-20
• Last updated: 2026-01-21

Locations

1 site across 1 country: Turkey (Türkiye)