NCT07351240

The Acupuncture Treatment Effect in Patients With Schizophrenia

The Quality of Life of Acupuncture Treatment Effect in Patients With Schizophrenia

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Calo Psychiatric Center · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Among various psychiatric disorders, this study focuses specifically on patients with schizophrenia. The aim of this study is to evaluate the therapeutic effects of acupuncture on antipsychotic medication-related side effects and psychiatric symptoms in patients with schizophrenia. This is a single-blind randomized study. Participants will be randomly assigned to one of two groups: Neiguan and Shenmen. Both the Neiguan and Shenmen groups will receive acupuncture treatment twice weekly, with each session lasting 30 minutes, for a total of four consecutive weeks. Assessments will be conducted prior to acupuncture intervention and after each acupuncture session. All assessment data will be collected and analyzed using statistical methods including descriptive statistics, chi-square tests, and t-tests. Generalized Estimating Equations (GEE-I) and multiple linear regression analyses will be applied to examine differences in psychological health, quality of life, and happiness before and after acupuncture intervention. It is anticipated that acupuncture will reduce antipsychotic-related side effects, improve psychiatric symptoms in patients with schizophrenia, and subsequently enhance patients' quality of life and happiness.

Conditions

• Mental Health

Interventions

Type	Name	Description
OTHER	Acupuncture	Both the Neiguan and Shenmen groups will receive acupuncture treatment twice weekly, with each session lasting 30 minutes, for a total of four consecutive weeks. Assessments will be conducted prior to acupuncture intervention and after each acupuncture session.

Timeline

• Start date: 2025-12-16
• Primary completion: 2026-07-31
• Completion: 2026-09-30
• First posted: 2026-01-20
• Last updated: 2026-01-22

Locations

1 site across 1 country: Taiwan