NCT07351019

Colonoscopy Bowel Prep Comparison Among Diabetic Patients

Colonoscopy Bowel Prep Comparison Among Diabetic Patients: Golytely v. SUPREP

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Eisenhower Army Medical Center · Federal
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if the Golytely or SUPREP bowel preparation works more effectively in bowel cleansing for colorectal cancer screening with colonoscopy in patients with diabetes. The main questions this study aims to answer are: 1. Is there a significant difference in bowel prep cleanse between Golytely and SUPREP in patients with diabetes based on the Boston Bowel Prep Score (BBPS) as assessed by blinded, skilled endoscopists? 2. Is there a significant difference in patients' tolerance between the bowel preparations as assessed by the validated Mayo Bowel Prep Tolerability Form (MBPTF)? Participants will: * Be randomized to take either Golytely or SUPREP bowel preparation prior to their colonoscopy * Complete the MBPTF on the procedure date prior to the scheduled colonoscopy * Undergo a standardized screening colonoscopy during which time a blinded endoscopist will document the participant's BBPS The research team hypothesizes that SUPREP will have a significant difference in tolerability (based on MBPTF), while exhibiting no difference in bowel cleanse (based on BBPS) in the diabetic patient population.

Conditions

• Colon Cancer Screening

Interventions

Type	Name	Description
DRUG	Golytely	Bowel cleanliness and patient tolerability
DRUG	SUPRPEP	Bowel cleanliness and patient tolerability

Timeline

• Start date: 2026-01-16
• Primary completion: 2026-07-28
• Completion: 2026-07-28
• First posted: 2026-01-20
• Last updated: 2026-01-20

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study