NCT07350447

Predictors of Laparoscopy Conversion in Adhesive Small Bowel Obstruction

Predictors of Laparoscopy Conversion in the Treatment of Adhesive Small Bowel Obstruction

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 170 (estimated)
• Sponsor: Almazov National Medical Research Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction. The main question it aims to answer is: are there any strong predictors of laparoscopy conversion in patients with small bowel obstruction, caused by intraabdominal adhesions.

Detailed description

Considering the undeniable advantages of laparoscopic interventions over laparotomic ones, the question of choosing a surgical approach in patients with acute adhesive intestinal obstruction can be reformulated as follows: in what situations is endovideosurgical intervention generally appropriate and feasible? A laparoscopic approach to severely distended bowel loops and widespread adhesions may increase the risk of serious complications. Indeed, some authors report intestinal injury in 6.3-26.9% of patients undergoing laparoscopic adhesiolysis for acute adhesive intestinal obstruction, which is statistically significantly higher than the same rate in patients operated on using a traditional approach. Therefore, a priority should be addressing the issue of adequately selecting patients who, based on a number of clinical indicators, are suitable for laparoscopic surgery or, at least, have no contraindications. While some parameters, such as acute cardiovascular or respiratory failure and pregnancy in the third trimester, can be defined as absolute contraindications to endovideosurgical access, a number of clinical and instrumental indicators are debatable. Despite the fact that this issue has been extensively covered in the literature, and the list of predictors of unsuccessful laparoscopic adhesiolysis is currently quite impressive, a standardized approach to access selection is lacking or is determined largely intuitively. The aim of this work is to determine reliable anamnestic, clinical and instrumental signs that would indicate a high risk of conversion of the laparoscopic intervention in patients with acute adhesive intestinal obstruction. The study is planned to be a multicenter, retrospective case-control study. Clinical data will be collected at four medical institutions in St. Petersburg. The medical records of patients who underwent emergency and urgent surgery for acute adhesive intestinal obstruction will be analyzed.

Conditions

• Adhesive Small Bowel Obstruction

Interventions

Type	Name	Description
PROCEDURE	Laparoscopic adhesiolysis	Dissection of intra-abdominal adhesions performed laparoscopically in accordance with the principles adopted in the medical institution.
PROCEDURE	Laparotomic adhesiolysis	Traditional adhesiolysis, performed via laparotomy after unsuccessfull attempt of endovideosurgical approach.

Timeline

• Start date: 2026-01-01
• Primary completion: 2026-04-30
• Completion: 2026-05-31
• First posted: 2026-01-20
• Last updated: 2026-01-20

Locations

7 sites across 1 country: Russia