NCT07347327

The Effect of Dual-target tACS Combined With Speech Training on Repetition Disorder After Stroke

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Ke Dong, MD · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial aims to study whether dual-target transcranial alternating current stimulation (tACS) applied to the auditory and motor brain region can improve repetition disorder in people with stroke, and to evaluate the safety of tACS. The main goals are to answer the following questions: 1. Can dual-tACS stimulation of the auditory and motor brain area improve repetition functions in people with aphasia after stroke? 2. Can it improve the integration of auditory information and speech motor control during communication? Researchers will compare the effects of real tACS versus sham (placebo) stimulation to see if real stimulation leads to better outcomes in aphasia patients. Participants will: 1. Receive one extra 20-minute session of either real or sham tACS each day for 10 days 2. Attend clinic visits before and after 10-days stimulation for clinical assessments(WAB) and fNIRS recording related brain activity

Conditions

• Aphasia

Interventions

Type	Name	Description
BEHAVIORAL	speech training	speech training(especially repetition training) synchronized with tACS stimulation
OTHER	real tACS	dual-target tACS on auditory and motor brain area at a frequency of 8 Hz,with individualized current intensity, delivered for 20 minutes.
OTHER	sham tACS	except for turning down the current intensity to zero during the 20-minute period, all other parameters are identical to those in real group.

Timeline

• Start date: 2023-01-01
• Primary completion: 2025-12-26
• Completion: 2025-12-29
• First posted: 2026-01-16
• Last updated: 2026-01-22

Locations

1 site across 1 country: China