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Trials / Enrolling By Invitation

Enrolling By InvitationNCT07346248

Postoperative Complications After Neoadjuvant Chemoradiotherapy or Short-course Radiotherapy and Total Neoadjuvant Treatment: a Multicentric Retrospective Cohort Study

Status
Enrolling By Invitation
Phase
Study type
Observational
Enrollment
266 (estimated)
Sponsor
Istituto Clinico Humanitas · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study is to compare the rate of postoperative complications between rectal cancer patients undergoing standard neoadjuvant chemoradiotherapy or short- course radiotherapy and patients receiving TNT. The secondary objectives of the study include the evaluation of treatment-related adverse reactions and postoperative complications in elderly patients receiving the treatments and the comparison of treatment-related adverse reactions and postoperative complications in patients receiving induction versus consolidation TNT.

Conditions

Interventions

TypeNameDescription
PROCEDUREChemoradiotherapyComparing

Timeline

Start date
2025-07-21
Primary completion
2026-07-31
Completion
2026-07-31
First posted
2026-01-16
Last updated
2026-01-16

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT07346248. Inclusion in this directory is not an endorsement.