NCT07345897

Emergency Department-based Cervical Cancer Screening Through Self-sampling

Advancing Cervical Cancer Screening Through Emergency Department-based Self-Sampling

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: University of Rochester · Academic / Other
• Sex: Female
• Age: 30 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.

Detailed description

This is a single-arm pilot trial with a prospectively enrolled sample. The participants who complete the screening survey and are determined to be adherent (n \~ 600) will be notified that they appear to be adherent with current screening guidelines, and their participation ends at this point. These participants will be considered screen failures for study purposes. Women and transgender/non-binary individuals with a cervix, aged 30-65, will be recruited from a high-volume urban ED. Follow-up will occur at 150 days to determine CC screening activity, perceived and concrete barriers to care, and participant experiences with the intervention. Electronic Health Record (EHR) review will be conducted to corroborate participants' reports of screening activities and assess completion of clinic-based testing and clinical endpoints.

Conditions

• HPV
• HPV Associated Cancers
• HPV Cancers
• Cervical Cancer Screening
• Cervical Cancer (Early Detection)

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cervical Cancer Screening	Subjects will perform self sampling for cervical cancer.

Timeline

• Start date: 2026-03-01
• Primary completion: 2027-08-01
• Completion: 2028-01-01
• First posted: 2026-01-16
• Last updated: 2026-01-16