Trials / Completed
CompletedNCT07344766
Treatment for Psychogenic Nonepileptic Seizures and Post-traumatic Stress Disorder Using Prolonged Exposure Therapy (PE) or Psychoeducation for PNES
Pilot Prolonged Exposure Teletherapy Treatment Trial for Psychogenic Nonepileptic Seizures (PNES) and Post-traumatic Stress Disorder (PTSD): A Randomized Clinical Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 44 (actual)
- Sponsor
- Northeast Regional Epilepsy Group · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
An outpatient randomized controlled clinical trial conducted at the Northeast Regional Epilepsy Group's PNES Program, involving mental health clinicians certified in PE and trained in administering PsychoEd.
Detailed description
A randomized parallel group trial was utilized to compare two therapeutic interventions for PNES, PE or PsychoEd, both delivered remotely via teletherapy. Each psychotherapeutic modality provided 12, 90-minute sessions. Seizure frequency was the primary outcome measure. Secondary outcome measures were depression (Beck Depression Inventory) and post-traumatic stress symptomatology (Post-Traumatic Disorder Diagnostic Scale and PTSD Checklist). Data was collected prospectively, including baseline measures before initiating treatment, upon treatment completion, and at follow-up intervals of 3, 6, and 12-months post-treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | imaginal and in vivo exposure | Prolonged exposure is a form of cognitive behavioral treatment that uses exposure to avoided memories and reminders |
| BEHAVIORAL | psychoeducation for psychogenic nonepileptic seizures | A combination of psychoeducation about PNES and skills for emotional regulation and relaxation. |
Timeline
- Start date
- 2020-11-16
- Primary completion
- 2025-05-12
- Completion
- 2025-05-30
- First posted
- 2026-01-15
- Last updated
- 2026-01-16
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT07344766. Inclusion in this directory is not an endorsement.