NCT07340450

Comparison of Oral vs Intravenous Iron Therapy for the Treatment of Postpartum Anemia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 122 (actual)
• Sponsor: Shahida Islam Medical Complex · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Postpartum anemia is a common condition associated with adverse maternal outcomes. This study aimed to compare the effectiveness of oral iron therapy versus intravenous iron therapy in women with postpartum anemia.

Detailed description

This randomized, open-label, parallel-group study was conducted at Shahida Islam Medical College and Hospital, Lodhran, Pakistan. Women diagnosed with postpartum anemia who fulfilled the eligibility criteria were randomly allocated using a lottery method to receive either intravenous iron (ferric carboxymaltose) or oral iron therapy (ferrous sulfate). The primary outcome was the change in hemoglobin level from baseline to 6 weeks of follow-up.

Conditions

• Postpartum Anaemia

Interventions

Type	Name	Description
DRUG	Ferric Carboxy Maltose	Participants received Intravenous iron i.e ferric carboxymaltose (≤1,000 mg) were given to patients in Group "A" either as a single dose or as two doses spaced three days apart in 100 milliliters of 0.9% normal saline during a half-hour period.
DRUG	Ferrous Sulfate	Participants given tablet Ferrous sulfate, 325 mg orally three times a day.

Timeline

• Start date: 2025-02-18
• Primary completion: 2025-08-18
• Completion: 2025-08-18
• First posted: 2026-01-14
• Last updated: 2026-01-14

Locations

1 site across 1 country: Pakistan