NCT07339202

Preoperative Hemodialysis Timing in Patients With End-Stage Kidney Disease: The POD-ESKD Pilot Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate the feasibility of two different preoperative hemodialysis schedules for people with end-stage kidney disease (ESKD) who undergo surgical procedures. The main questions it aims to answer are: Is it feasible to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis? Is it safe to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis? Researchers will compare the two hemodialysis schedules to see if the scheduling and safety profiles are the same. Participants will: Answer questions about their health up to 4 weeks before and 4 weeks after the surgical procedure. Receive hemodialysis on the day of the surgical procedure or not, depending on the study treatment assignment.

Detailed description

Participants will participate in the study for approximately 2 months, including assessment of 30-day postoperative outcomes.

Conditions

• Perioperative Management
• End Stage Kidney Disease (ESRD)
• Hemodialysis

Interventions

Type	Name	Description
PROCEDURE	Same-Day Hemodialysis	Hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure (typically in the morning prior to the procedure).
PROCEDURE	No Same-Day Hemodialysis	No hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure.

Timeline

• Start date: 2026-04-16
• Primary completion: 2027-09-15
• Completion: 2027-10-15
• First posted: 2026-01-14
• Last updated: 2026-03-27

Locations

1 site across 1 country: United States