NCT07336576

Treatment Strategy for Adult Congenital Biliary Dilation

Surgery-Oriented Classification and Treatment Strategy for Adult Congenital Biliary Dilation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 234 (actual)
• Sponsor: Beijing Tsinghua Chang Gung Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The management of congenital biliary dilations (CBDs), including choledochal cysts, represents one of the most challenging areas in hepatobiliary surgery due to their potential implications for long-term morbidity and malignant transformation. While CBDs have a relatively low incidence in Western populations (1/150,000-1/100,000), the prevalence is notably higher in Asian countries (1/1,000), making it a significant global health concern. Although complete surgical resection remains the standard of care, the optimal extent of resection and reconstruction strategy, particularly for complex disease patterns, continues to be debated. To address these challenges, the current study proposes a novel surgery-oriented classification system for adult CBD based on the analysis of 234 consecutive cases.

Conditions

• Congenital Biliary Dilation

Interventions

Type	Name	Description
PROCEDURE	hepatectomy、liver transplantation、hepaticojejunostomy	resection of the diseased bile duct, elimination of secondary lesions, and restoration of biliary-enteric continuity.

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-06-01
• Completion: 2025-07-01
• First posted: 2026-01-13
• Last updated: 2026-01-13

Locations

1 site across 1 country: China