NCT07334262

A Study to Evaluate the Food Effect on RNK08954 in Healthy Participants, and the Mass Balance Study of [14C]RNK08954 in Healthy Adult Male Subjects

A Study to Evaluate the Food Effect on the Pharmacokinetics of RNK08954 Tablets and to Assess the Mass Balance of [14C]RNK08954 in Healthy Adult Male Subjects in China

• Status: Not Yet Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Ranok Therapeutics (Hangzhou) Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

An Study of Orally Administered RNK08954 in Healthy Adult Subjects to Determine the Effect of Food on the Pharmacokinetics of RNK08954，Mass Balance Study of \[14C\] RNK08954 in Chinese Healthy Adult Male Subjects

Conditions

• Food Effect
• Mass Balance

Interventions

Type	Name	Description
DRUG	RNK08954	KRAS G12D inhibitor

Timeline

• Start date: 2025-12-31
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2026-01-12
• Last updated: 2026-01-14

Locations

1 site across 1 country: China