NCT07333833

Development and Validation of an Early Prediction Model for Severe Mycoplasma Pneumoniae Pneumonia in Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 964 (actual)
• Sponsor: Beijing Friendship Hospital · Academic / Other
• Sex: All
• Age: 1 Month – 14 Years
• Healthy volunteers: Not accepted

Summary

Pneumonia is a major threat to the health of children. Mycoplasma pneumoniae infection is a core cause of pediatric pneumonia, and the incidence of severe mycoplasma pneumoniae pneumonia (SMPP) has increased in recent years. SMPP leads to a range of extrapulmonary symptoms, including myocardial and liver injury, which may be life-threatening. Therefore, there is an urgent need to establish an early warning model for SMPP to improve the prognosis of pediatric pneumonia. This observational study aims to establish a early prediction model of SMPP. Development cohorts are enrolled from Beijing Friendship Hospital between 2018-1-1 to 2024-5-31, and validation cohorts are enrolled between 2024-6-1 to 2025-6-30.

Conditions

• Mycoplasma Pneumoniae Pneumonia

Interventions

Type	Name	Description
OTHER	medical history taking, blood test, pulmonary ultrasound	medical history taking, blood test, pulmonary ultrasound are used for MPP and SMPP diagnosis

Timeline

• Start date: 2018-01-01
• Primary completion: 2025-06-30
• Completion: 2025-06-30
• First posted: 2026-01-12
• Last updated: 2026-01-12

Locations

1 site across 1 country: China