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RecruitingNCT07327840

Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a)

A Double-blind, Randomized, Placebo-controlled Phase 2 Study to Evaluate Efficacy and Safety of Kylo-11 in Participants With Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a)

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
204 (estimated)
Sponsor
Kylonova (Xiamen) Biopharma co., LTD. · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This is a phase 2, double-blind, randomized, placebo-controlled, multi-center, dose-finding study to evaluate the efficacy and safety of Kylo-11 administered subcutaneously compared to placebo in participants with ASCVD and elevated Lp(a).

Conditions

Interventions

TypeNameDescription
DRUGKylo-11 or matched placeboAdministered subcutaneously

Timeline

Start date
2025-10-29
Primary completion
2027-02-28
Completion
2028-08-31
First posted
2026-01-08
Last updated
2026-03-23

Locations

43 sites across 1 country: China

Source: ClinicalTrials.gov record NCT07327840. Inclusion in this directory is not an endorsement.

Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a) (NCT07327840) · Clinical Trials Directory