NCT07322809

Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients

Association Between Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients: A Prospective Longitudinal Data Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 4,417 (actual)
• Sponsor: Chinese PLA General Hospital · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Frailty is a key predictor of adverse outcomes in older surgical patients, yet its longitudinal evolution and potentially reversible nature remain underexplored in perioperative settings. This study aimed to characterize postoperative frailty trajectories in older patients and to examine their association with one-year mortality, as well as factors influencing trajectory group.

Conditions

• Frailty in Older Adults
• All Cause Mortality
• Trajectory

Timeline

• Start date: 2020-04-01
• Primary completion: 2022-04-30
• Completion: 2023-04-30
• First posted: 2026-01-07
• Last updated: 2026-01-09

Locations

1 site across 1 country: China