NCT07321275

Ultra-early Chest CT for SAP Prediction

Ultra-early Chest CT Improves Risk Prediction of Stroke-associated Pneumonia: Model Development and External Validation in a Multicentre Retrospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,499 (actual)
• Sponsor: Capital Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Stroke-associated pneumonia (SAP) is a common and serious complication after acute ischaemic stroke (AIS). Existing scores rely mainly on clinical variables, and the added prognostic value of inflammatory markers and early chest CT findings remains uncertain. We developed and externally validated an early multimodal model combining clinical severity, inflammation, and chest CT abnormalities, and explored risk-stratified associations between prophylactic antibiotics and SAP.

Conditions

• Acute Ischaemic Stroke
• Stroke-associated Pneumonia

Timeline

• Start date: 2026-01-15
• Primary completion: 2026-02-19
• Completion: 2026-02-19
• First posted: 2026-01-07
• Last updated: 2026-03-10

Locations

8 sites across 1 country: China