NCT07320781

Role of Preoperative Tapentadol in Reduction of Perioperative Analgesic Requirement After Breast Conservative Surgery in Cancer Patients.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Shaukat Khanum Memorial Cancer Hospital & Research Centre · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study evaluated the preemptive analgesic efficacy of Tapentadol in reducing peri operative analgesic requirements among patients undergoing breast cancer surgery.

Detailed description

A double blinded prospective RCT was conducted with 70 patients undergoing breast cancer surgery with 35 patients being studied with Administrated drug \& other 35 as placebo. Intraoperative \& postoperative morphine consumption was calculated and documented.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DRUG	Tapentadol	75 mg oral tapentadol given 1 hour before surgery in control group and placebo tablet was given in Group B. Intraoperative and post operative morphine consumption and pain scores at 1,2,3,4 hours were calculated.
OTHER	Placebo	Placebo tablet was given in group B.

Timeline

• Start date: 2024-11-15
• Primary completion: 2025-09-30
• Completion: 2025-10-10
• First posted: 2026-01-06
• Last updated: 2026-01-08

Locations

1 site across 1 country: Pakistan