NCT07319546

Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty

Effectiveness of Accelerated Rehabilitation on Knee Joint Function and Quality of Life in Individuals With Total Knee Arthroplasty: A Double Blind Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to conventional rehabilitation in Dali, Yunan, China. The study will include patients aged 50-80 years who are scheduled for primary unilateral TKA. Participants will be randomly assigned to either an accelerated rehabilitation group or conventional rehabilitation group. The primary outcomes will include knee joint function, assessed using the KOOS and quality of life measures using the SF-36 surveys. The study will follow participants for 6 months post-surgery to assess longer-term outcomes. This study will not include individuals undergoing revision TKA or those with severe comorbid conditions. The results will provide critical insights into the role of accelerated rehabilitation in improving post-operative recovery, functional outcomes, and overall quality of life for TKA patients.

Conditions

• Knee Osteoarthristis
• Arthroplasties, Knee Replacement

Interventions

Type	Name	Description
BEHAVIORAL	Accelerated exercise	Based on optimal and accelerated concepts
BEHAVIORAL	Routine exercise	Conventional program

Timeline

• Start date: 2025-12-01
• Primary completion: 2026-12-30
• Completion: 2027-06-30
• First posted: 2026-01-06
• Last updated: 2026-01-06

Locations

1 site across 1 country: China