NCT07318285

Targeted Lidocaine Infusion for Pain Reduction in Office Hysteroscopy

A Modified Technique of Target Lidocaine Infusion for Pain Control in Office Hysteroscopy: A Double-Blind Randomized Controlled

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 208 (estimated)
• Sponsor: YAARA TABIB · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to find out whether a small amount of lidocaine (a common local anesthetic) can reduce pain during office hysteroscopy - a procedure used to look inside the uterus. The study will compare lidocaine to saline (salt water) to see which one helps more with pain relief. Participants will: 1. Receive either lidocaine or saline gently applied inside the cervix right before the procedure 2. Undergo the hysteroscopy as planned 3. Be asked to rate their pain and satisfaction after the procedure Lidocaine is commonly and safely used in dental and gynecological procedures. Participation is voluntary, and the procedure itself will not change.

Conditions

• Hysteroscopy / Methods
• Lidocaine Infusion
• Placebo - Control

Interventions

Type	Name	Description
DRUG	Lidocaine %2 ampoule	A 5 mL dose of 2% lidocaine solution will be infused slowly through the internal os using the hysteroscope before the start of uterine cavity distension.
OTHER	Saline (0.9% NaCl)	A 5 mL dose of sterile normal saline will be infused slowly through the internal os using the same technique as in the intervention arm, immediately before cavity distension.

Timeline

• Start date: 2026-02-01
• Primary completion: 2028-12-30
• Completion: 2029-12-30
• First posted: 2026-01-05
• Last updated: 2026-01-05