NCT07317128

Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity

Study to Evaluate the Efficacy of Two Occlusion Technology Dentifrices in the Relief of Dentinal Hypersensitivity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: HALEON · Industry
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare the clinical efficacy of test fluoride dentifrice in reducing Dentin Hypersensitivity (DH) with that of a standard fluoride dentifrice, as measured by evaporative air sensitivity after 12 weeks twice daily brushing.

Detailed description

A randomized, examiner blind, three treatment arm, parallel group design with a treatment period of 12 weeks. Approximately 275 participants will be screened to ensure that approximately 120 participants to be randomized (approximately 40 to each treatment group) and at least 114 participants to complete the study (approximately 38 per treatment group).

Conditions

• Dentin Sensitivity

Interventions

Type	Name	Description
DRUG	Test Dentifrice	Dentifrice containing 1450 parts per million (ppm) fluoride as sodium monofluorophosphate.
DRUG	Colgate Sensitive ProRelief	A marketed dentifrice.
DRUG	Colgate Triple Protection	A marketed dentifrice.

Timeline

• Start date: 2013-01-20
• Primary completion: 2013-06-08
• Completion: 2013-06-08
• First posted: 2026-01-05
• Last updated: 2026-01-05

Locations

1 site across 1 country: China